Is their a long term risk of developing type 2 diabetes following a pregnancy complicated by gestational diabetes (GDM)?
From: Diabetes Care
- Lee, A.J., Hiscock, R.J., Wein, P., Walker, S.P., Permezel, M., 2007. Gestational Diabetes Mellitus: Clinical Predictors and Long-Term Risk of Developing Type 2 Diabetes A retrospective cohort study using survival analysis. Dia Care 30, 878–883.
- 5,470 patients with gestational diabetes and 783 control subjects
A study of participants who presented for postnatal follow-up between 1971 and 2003.
- Risk of developing diabetes increased with time for both groups and was 9.6 times greater for patients with GDM.
- The cumulative risk of developing type 2 diabetes for the GDM patients was 25.8% at 15 years post-diagnosis.
- Predictive factors for the development of type 2 diabetes were use of insulin (hazard ratio x3.5), Asian origin compared with Caucasian (x2.1), and 1-h blood glucose (x1.3 for every 1 mmol increase above 10.1 mmol).
- BMI was associated with an increased risk of developing type 2 diabetes.
- Yes (with confidence)