Does quality of life decrease three years after diagnosis of localised prostate cancer?

From: BMJ

Journal rating:
rating: 99%
Study Quality:
rating: 55%

Overall Reliability

Article Quality:
rating: 65%
rating: 50%


  • 1,642 men


  • Men with localised prostate cancer were eligible if aged less than 70 years, diagnosed between October 2000 and October 2002, and notified to the New South Wales central cancer registry. 495 controls were randomly selected from the New South Wales electoral roll and matched to cases by age and postcode.
  • Health specific and disease specific function was evaluated up to three years after diagnosis via the Los Angeles prostate cancer index.


  • Sexual dysfunction three years after diagnosis was common in all treatment groups, whereas poor urinary function was less common.
  • Bowel function was most compromised in those who had external beam radiotherapy.


  • Yes (with confidence)


Editors Notes

  • Five year survival for localised prostate cancer is almost 100% in Australia and the United States.
  • Observational studies show that different treatment options offer nearly equal survival rates; therefore, quality of life after treatment should be a major consideration in treatment decision making.