Does low consumption of sea food in early pregnancy create a higher risk of preterm delivery?
- Olsen, S.F., 2002. Low consumption of seafood in early pregnancy as a risk factor for preterm delivery: prospective cohort study. BMJ 324, 447–450.
- 8,729 pregnant women.
Participants receiving routine antenatal care were asked to complete a self administered questionnaire in weeks 16 and 30 of gestation.
- The occurrence of preterm delivery differed significantly across four groups of seafood intake, falling progressively from 7.1% in the group never consuming fish to 1.9% in the group consuming fish twice/week.
- Odds for preterm delivery were increased by a factor of 3.6 in the zero consumption group compared with the highest consumption group.
- Low consumption of fish was a strong risk factor for preterm delivery and low birth weight.
- The associations were strongest below a daily intake of 0.15 g long chain n-3 fatty acids or 15 g fish.
- Yes (with confidence)
- The authors recommend that in women with zero or low intake of fish, small amounts of n-3 fatty acids—provided as fish or fish oil—may provide protection against preterm delivery and low birth weight.