Does fish intake lower the risk of acute coronary syndrome?

From: European Heart Journal

Journal rating:
rating: 99%
Study Quality:
rating: 55%

Overall Reliability

Article Quality:
rating: 35%
rating: 75%


  • 57,053 men and women between 50 and 64 years.


  • Intake of lean and fatty fish was estimated from a detailed and validated food frequency questionnaire.
  • Potential cases of acute coronary syndrome were identified through nationwide medical databases. 


  • Among men, intake of fatty fish was associated with a 30% lower risk of acute coronary syndrome.
  • The benefits were observed for intakes >6 g of fatty fish per day with no obvious additional benefit observed for higher intakes.
  • The results were not consistent in women.


  • Yes (with confidence) – benefits seen in men only.


Editors Notes

  • A very low incidence of coronary heart disease (CHD) was reported in Greenland Eskimos more than 35 years ago which was believed to be due to their extremely high intake of seafood rich in n-3 polyunsaturated fatty acids (PUFA).
  • Since then, data from other populations with a very high intake of seafood such as Alaskan Natives and Japanese fishermen have supported the hypothesis that marine n-3 PUFA may protect against atherosclerosis, thrombosis, and CHD.