Does a low carbohydrate diet increase the risk of coronary heart disease in women?
- Halton, T.L., Willett, W.C., Liu, S., Manson, J.E., Albert, C.M., Rexrode, K., Hu, F.B., 2006. Low-carbohydrate-diet score and the risk of coronary heart disease in women. N. Engl. J. Med. 355, 1991–2002.
- 82,802 women
Data from a questionnaire was used to calculate a low-carbohydrate-diet score, which was based on the percentage of energy as carbohydrate, fat, and protein.
- During 20 years of follow-up, the authors documented 1,994 new cases of coronary heart disease.
- A low-carbohydrate diet was not associated with a risk of coronary heart disease.
- When vegetable sources of fat and protein were chosen, the low-carbohydrate-diet score was associated with a moderately lower risk of coronary heart disease than when animal sources were chosen.
- A higher glycemic load was strongly associated with an increased risk of coronary heart disease
- No (with confidence)