Can we determine the most effective antibiotics for treating pneumonia in children?
From: The Cochrane Collaboration
- Kabra, S.K., Lodha, R., Pandey, R.M., 1996. Antibiotics for community-acquired pneumonia in children, in: Cochrane Database of Systematic Reviews. John Wiley & Sons, Ltd.
- 27 studies including 11,928 children
- The paper is a systematic review / meta analysis of all relevant trials.
- This means that the data from all similar trials has been grouped to form an overall outcome.
- For outpatient treatment of pneumonia, amoxycillin is an alternative treatment to co-trimoxazole.
- Oral amoxycillin in hospitalised children with severe pneumonia without hypoxia (decreased level of oxygen) may be effective.
- For very severe pneumonia, a combination of penicillin or ampicillin and gentamycin is more effective than chloramphenicol alone.
- Yes (with confidence)
Pneumonia is the leading cause of mortality in children under five years of age. Most cases of community-acquired pneumonia in low-income countries are caused by bacteria.