Are weight-reducing diets effective treatments on cardiovascular morbidity, blood pressure, weight loss and early mortality in hypertensive patients?

From: The Cochrane Collaboration

Journal rating:
rating: 98%
Study Quality:
rating: 100%
%

Overall Reliability

Article Quality:
rating: 65%
Partcipants
rating: 50%

Participants/situation

  • 2,100 participants across 8 trials.

Study

  • The paper is a systematic review / meta analysis of all relevant trials.
  • This means that the data from all similar trials has been grouped to form an overall outcome.

Results

  • Average treatment duration was 6 to 36 months.
  • No study included mortality as a pre-defined outcome.
  • In three of eight studies, effects on systolic and diastolic blood pressure were provided, showing that systolic and diastolic blood pressure were reduced by weight loss interventions by 4.5 mm Hg and 3.2 mm Hg, respectively.
  • Five out of eight studies reported body weight, and weight loss interventions reduced weight by 4.0 kg as compared to controls.
  • No useful information on possible adverse effects was reported in the included trials.

Answer

  • Yes (with confidence); for blood pressure and weight loss.
  • Undecided; effect on mortality or adverse outcomes.

i

Keywords