Are antihypertensive drugs effective for people with mild hypertension?

From: The Cochrane Collaboration

Journal rating:
rating: 98%
Study Quality:
rating: 100%

Overall Reliability

Article Quality:
rating: 75%
rating: 50%


  • 4 trials with 8,912 participants


  • The paper is a systematic review / meta analysis of all relevant trials.
  • This means that the data from all similar trials has been grouped to form an overall outcome.


  • Treatment for 4 to 5 years with antihypertensive drugs did not reduce the likihood of premature death.
  • Treatment did not reduce the likelihood of coronary heart disease, stroke, or total cardiovascular events.
  • 9% of participants withdrew from the trials due to the adverse side effects of the antihypertensive drugs.


  • No (without confidence)


Editors Notes

  • Antihypertensive drugs are used in the treatment of adults (primary prevention) with mild hypertension (systolic BP 140-159 mmHg and/or diastolic BP 90-99 mmHg)