Are antihypertensive drugs effective for people with mild hypertension?

From: The Cochrane Collaboration

Journal rating:
rating: 98%
Study Quality:
rating: 100%
%

Overall Reliability

Article Quality:
rating: 75%
Partcipants
rating: 50%

Participants/situation

  • 4 trials with 8,912 participants

Study

  • The paper is a systematic review / meta analysis of all relevant trials.
  • This means that the data from all similar trials has been grouped to form an overall outcome.

Results

  • Treatment for 4 to 5 years with antihypertensive drugs did not reduce the likihood of premature death.
  • Treatment did not reduce the likelihood of coronary heart disease, stroke, or total cardiovascular events.
  • 9% of participants withdrew from the trials due to the adverse side effects of the antihypertensive drugs.

Answer

  • No (without confidence)

i

Editors Notes

  • Antihypertensive drugs are used in the treatment of adults (primary prevention) with mild hypertension (systolic BP 140-159 mmHg and/or diastolic BP 90-99 mmHg) 

Keywords