Are antihypertensive drugs effective for people with mild hypertension?
From: The Cochrane Collaboration
- Diao, D., Wright, J.M., Cundiff, D.K., Gueyffier, F., 1996. Pharmacotherapy for mild hypertension, in: Cochrane Database of Systematic Reviews. John Wiley & Sons, Ltd.
- 4 trials with 8,912 participants
- The paper is a systematic review / meta analysis of all relevant trials.
- This means that the data from all similar trials has been grouped to form an overall outcome.
- Treatment for 4 to 5 years with antihypertensive drugs did not reduce the likihood of premature death.
- Treatment did not reduce the likelihood of coronary heart disease, stroke, or total cardiovascular events.
- 9% of participants withdrew from the trials due to the adverse side effects of the antihypertensive drugs.
- No (without confidence)
- Antihypertensive drugs are used in the treatment of adults (primary prevention) with mild hypertension (systolic BP 140-159 mmHg and/or diastolic BP 90-99 mmHg)